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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK7
All Species:
26.06
Human Site:
S251
Identified Species:
38.22
UniProt:
P50613
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50613
NP_001790.1
346
39038
S251
P
D
Y
V
T
F
K
S
F
P
G
I
P
L
H
Chimpanzee
Pan troglodytes
XP_518193
305
34323
A222
P
L
H
H
I
F
S
A
A
G
D
D
L
L
D
Rhesus Macaque
Macaca mulatta
XP_001092242
346
39008
S251
P
D
Y
V
T
F
K
S
F
P
G
I
P
L
H
Dog
Lupus familis
XP_850424
354
39795
S259
P
D
F
V
T
F
K
S
F
P
G
I
P
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q03147
346
38950
S251
P
D
Y
V
T
F
K
S
F
P
G
V
P
L
Q
Rat
Rattus norvegicus
P51952
329
37122
S243
P
D
Y
V
T
F
K
S
F
P
G
I
P
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506541
324
36280
S229
P
D
Y
V
T
F
K
S
F
P
G
T
P
L
P
Chicken
Gallus gallus
P13863
303
34670
G221
F
R
I
F
R
A
L
G
T
P
N
N
D
V
W
Frog
Xenopus laevis
P20911
352
39672
S257
P
D
Y
V
A
F
K
S
F
P
G
T
P
L
H
Zebra Danio
Brachydanio rerio
A8WIP6
344
39006
F242
P
D
Y
N
K
I
T
F
K
E
N
P
P
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511044
353
39655
N251
H
D
Y
L
Q
F
R
N
F
P
G
T
P
L
D
Honey Bee
Apis mellifera
XP_395800
321
36188
P230
P
D
F
I
Q
F
K
P
F
P
G
T
P
L
K
Nematode Worm
Caenorhab. elegans
P34556
332
38277
V249
T
E
L
E
W
N
G
V
E
S
L
P
D
Y
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
F214
D
S
E
I
D
E
L
F
K
I
F
R
I
L
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT0
391
44511
F248
P
D
Y
V
E
Y
Q
F
V
P
A
P
S
L
R
Baker's Yeast
Sacchar. cerevisiae
P06242
306
35228
T225
F
R
A
L
G
T
P
T
D
R
D
W
P
E
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
99.7
92.6
N.A.
95
91
N.A.
87.5
39.8
85.2
42.2
N.A.
65.7
63.8
39.3
N.A.
Protein Similarity:
100
88.1
99.7
95.4
N.A.
96.8
92.4
N.A.
88.7
56.3
90.3
59.5
N.A.
78.4
75.1
57.5
N.A.
P-Site Identity:
100
20
100
86.6
N.A.
86.6
93.3
N.A.
86.6
6.6
86.6
26.6
N.A.
53.3
60
0
N.A.
P-Site Similarity:
100
33.3
100
93.3
N.A.
93.3
93.3
N.A.
86.6
13.3
86.6
33.3
N.A.
73.3
73.3
6.6
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
49.1
41
N.A.
Protein Similarity:
N.A.
57.8
N.A.
65.2
60.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
0
7
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
69
0
0
7
0
0
0
7
0
13
7
13
0
13
% D
% Glu:
0
7
7
7
7
7
0
0
7
7
0
0
0
7
0
% E
% Phe:
13
0
13
7
0
63
0
19
57
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
7
7
0
7
57
0
0
0
7
% G
% His:
7
0
7
7
0
0
0
0
0
0
0
0
0
0
19
% H
% Ile:
0
0
7
13
7
7
0
0
0
7
0
25
7
7
0
% I
% Lys:
0
0
0
0
7
0
50
0
13
0
0
0
0
0
13
% K
% Leu:
0
7
7
13
0
0
13
0
0
0
7
0
7
75
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
7
0
7
0
0
13
7
0
0
0
% N
% Pro:
69
0
0
0
0
0
7
7
0
69
0
19
69
0
13
% P
% Gln:
0
0
0
0
13
0
7
0
0
0
0
0
0
0
19
% Q
% Arg:
0
13
0
0
7
0
7
0
0
7
0
7
0
0
7
% R
% Ser:
0
7
0
0
0
0
7
44
0
7
0
0
7
0
0
% S
% Thr:
7
0
0
0
38
7
7
7
7
0
0
25
0
0
0
% T
% Val:
0
0
0
50
0
0
0
7
7
0
0
7
0
7
7
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
7
% W
% Tyr:
0
0
57
0
0
7
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _